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Baron-Cohen's work in systemising-empathising led him to investigate whether higher levels of fetal testosterone explain the increased prevalence of autism spectrum disorders among males; [17] his theory is known as the " extreme male brain " theory of autism. [11] A review of his book The Essential Difference published in Nature in 2003 summarises his proposal as: "the male brain is programmed to systemize and the female brain to empathize ... Asperger's syndrome represents the extreme male brain". [19] Critics say that because his work has focused on higher-functioning individuals with autism spectrum disorders, it requires independent replication with broader samples. [20] His prediction that prenatal testosterone would be elevated in autism has been confirmed. [21]

After years of JDRF advocacy efforts, The Centers for Medicare & Medicaid Services (CMS) classifies continuous glucose monitors (CGMs) as durable medical equipment, creating a pathway for their coverage by Medicare. However, CMS did not establish coverage criteria for CGM in their ruling, so Medicare coverage decisions will be made on a case-by-case or claim-by-claim basis based on a determination of whether CGM is “reasonable and necessary” for treatment of an individual’s T1D. The new classification is crucial for continued development of artificial pancreas systems, most of which incorporate CGMs.

Their effect on muscle fibers and the tendency to cause fatigue brings up the topic of exercise and whether statins make it more difficult to execute a work-out routine. There are anecdotes about patients who think statins harm their athletic performance, but formal establishment of an effect is not so clear . A recently published study showed that rats given statins were not able to run as far as rats without the drug. Analysis of the muscle showed animals on the medicine had less glycogen and there was evidence of mitochondrial damage. Mitochondria are the parts of the cells that burn fuel for energy. If statin use makes exercise more difficult and less fun, it could inadvertently lead patients to become more sedentary, which is the opposite of what is desired. Increasing concerns about muscle-related adverse events are leading to the idea that lower doses of statins should be prescribed than current practice.

Primo high dose

primo high dose


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