Like other AAS, drostanolone is an agonist of the androgen receptor (AR).  It is not a substrate for 5α-reductase and is a poor substrate for 3α-hydroxysteroid dehydrogenase (3α-HSD), and therefore shows a high ratio of anabolic to androgenic activity.  As a DHT derivative, drostanolone is not a substrate for aromatase and hence cannot be aromatized into estrogenic metabolites .  While no data are available on the progestogenic activity of drostanolone, it is thought to have low or no such activity similarly to other DHT derivatives.  Since the drug is not 17α-alkylated , it is not known to cause hepatotoxicity . 
Just like any other oral steroid, Methyl Drostanolone must also be taken in the right dose with proper guidance. Abusing Methyl Drostanolone would cause devastating negative impacts on the users. Taking Methyl Drostanolone for extended period of time would make the side effects permanent and irreversible. The most effective and recommended dose of Methyl Drostanolone for men is 20mg to 40mg per day. The duration of cycle should not exceed the period of 6 weeks. Taking Methyl Drostanolone for more than 6 weeks would cause major adverse effects on the liver. The dose must not exceed the 40mg per day dosage. Higher doses are found to stress the liver significantly. Methyl Drostanolone is found to be abused mostly and later on the users have reported significant liver toxic issues.