In either case, both men and women, Anavar can be used for far longer than most oral anabolic steroids due to its low liver toxicity rating and further as it does not appear to taper off in benefit as fast as many other oral anabolic steroids. The majority of Anavar users will supplement for 6-8 weeks but longer durations of 12 weeks are not uncommon, especially during female contest preparation time. Keep in mind, the leaner you are the greater the results will be, meaning, they will be far more pronounced; for this reason most women will choose Anavar during the latter half of their diet to reap the greatest reward.
Prostaglandins are synthesized from arachidonate(Lipoxygenase which catalyze the dioxygenation of polyunsaturated fatty acids) in the cell membrane by the action of phospholipase A2. Cyclooxygenase and lipoxygenase pathways, compete with one another to form prostaglandins(as well as thromboxane or leukotriene-leukotriene being a bronchial stimulator),
In the cyclooxygenase pathway, the prostaglandins D, E and F plus thromboxane and prostacyclin are made. Thromboxanes are made in platelets and cause constriction of vascular smooth muscle and platelet aggregation
Leukotrienes are made in leukocytes and macrophages via the lipoxygenase pathway. They are potent constrictors of the bronchial airways. They are also important in inflammation and hypersensitivity reactions as they increase vascular permeability.