Used for thousands of years - Boswellic acid is known to exert anti-inflammatory effects. It is thought that by preventing the breakdown of connective tissue, and by increasing the blood supply to joint tissues, Boswellic acts as an anti-inflammatory. In fact, in one study, Boswellia performed better than prescription drugs at reducing the inflammation of osteo and rheumatory arthritis. It also sometimes performs better than aspirin, acetaminophen and other NSAIDS (non-steroidal anti-inflammatory aides) at reducing general arthritis pain.
Although deaths from methadone are on the rise, methadone-associated deaths are not being caused primarily by methadone intended for methadone treatment programs, according to a panel of experts convened by the Substance Abuse and Mental Health Services Administration , which released a report titled "Methadone-Associated Mortality, Report of a National Assessment". The consensus report concludes that "although the data remains incomplete, National Assessment meeting participants concurred that methadone tablets or diskettes distributed through channels other than opioid treatment programs most likely are the central factors in methadone-associated mortality." 
After the Kefauver Harris Amendment was passed in 1962, the . FDA began the DESI review process to ensure the safety and efficacy of drugs approved under the more lenient pre-1962 standards, including Dianabol.  In 1965, the FDA pressured CIBA to further document its legitimate medical uses, and re-approved the drug for treating post-menopausal osteoporosis and pituitary-deficient dwarfism .  After CIBA's patent exclusivity period lapsed, other manufacturers began to market generic metandienone in the .